| Foreword by Professor Sir Magdi Yacoub | ||
| Identity | ||
| Teaching | ||
| Funding | ||
| History | ||
| Management Structure | ||
| How to reach us | ||
| Seminars | ||
| Student Presentation Day 2006 | ||
| Bioengineering the Heart - Royal Society | ||
| New Collaboration with EMBL | ||
Al Mohanna F, Collison K, Parhar R, Kwaasi A, Meyer B, Saleh S, Allen S, al Sedairy S, Stern D, & Yacoub M (1997). Activation of naive xenogeneic but not allogeneic endothelial cells by human naive neutrophils: a potential occult barrier to xenotransplantation. Am J Pathol 151 , 111-120. Allen S, Anastasiou N, Royston D, Paniagua R, & Yacoub M (1997). Effect of aprotinin on vascular reactivity of coronary bypass grafts. J Thorac Cardiovasc Surg 113 , 319-326. Amrani M, Gray CC, Smolenski RT, Goodwin AT, London A, & Yacoub MH (1997). The effect of L-arginine on myocardial recovery after cardioplegic arrest and ischemia under moderate and deep hypothermia. Circulation 96 , II-9. Anastasiou N, Allen S, Paniagua R, Chester A, & Yacoub M (1997). Altered endothelial and smooth muscle cell reactivity caused by University of Wisconsin preservation solution in human saphenous vein. J Vasc Surg 25 , 713-721. Barbir M, Lazem F, Bowker T, Ludman P, Banner N, Mitchell A, & Yacoub M (1997). Determinants of transplant-related coronary calcium detected by ultrafast computed tomography scanning. Am J Cardiol 79 , 1606-1609. Barbir M, Lazem F, Banner N, Mitchell A, & Yacoub M (1997). The prognostic significance of non-invasive cardiac tests in heart transplant recipients. European Heart Journal 18 , 692-696. Barton PJ, Townsend PJ, Brand NJ, & Yacoub MH (1997). Localization of the fast skeletal muscle troponin I gene (TNNI2) to 11p15.5: genes for troponin I and T are organized in pairs. Annals of Human Genetics 61 ( Pt 6) , 519-523. Batten P, McCormack A, Yacoub M, & Rose M (1997). Effect of cyclosporine A and FK 506 on human T cell responses to xenogeneic and allogeneic endothelium: relative resistance of T cell/porcine endothelial interactions. Transplant Proc 29 , 907-908. Belvisi MG, Saunders MA, Haddad e, Hirst SJ, Yacoub MH, Barnes PJ, & Mitchell JA (1997). Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type. Br J Pharmacol 120 , 910-916. Birks EJ & Yacoub MH (1997). The role of nitric oxide and cytokines in heart failure. Coron Artery Dis 8 , 389-402. Boateng S, Seymour AM, Dunn M, Yacoub M, & Boheler K (1997). Inhibition of endogenous cardiac phosphatase activity and measurement of sarcoplasmic reticulum calcium uptake: a possible role of phospholamban phosphorylation in the hypertrophied myocardium. Biochem Biophys Res Commun 239 , 701-705. Brand NJ (1997). Myocyte enhancer factor 2 (MEF2). Int J Biochem Cell Biol 29 , 1467-1470. Bullo B, Marlewski M, Manitius J, Smolenski RT, & Rutkowski B (1997). [The levels of adenine nucleotides and hypoxanthine in blood of patients on long-term hemodialysis using dialysis fluid containing acetate or bicarbonate]. Przegl Lek 54 , 3-5. Dunn MJ (1997). Quantitative two-dimensional gel electrophoresis: from proteins to proteomes. Biochem Soc Trans 25 , 248-254. Dunn MJ, Corbett JM, & Wheeler CH (1997). HSC-2DPAGE and the two-dimensional gel electrophoresis database of dog heart proteins. Electrophoresis 18 , 2795-2802. Dunn MJ (1997). Electroblotting of proteins from polyacrylamide gels for chemical characterization. Methods Mol Biol 64 , 37-42. Dunn MJ (1997). Two-dimensional polyacrylamide gel electrophoresis for the separation of proteins for chemical characterization. Methods Mol Biol 64 , 25-36. Evans G, Wheeler CH, Corbett JM, & Dunn MJ (1997). Construction of HSC-2DPAGE: a two-dimensional gel electrophoresis database of heart proteins. Electrophoresis 18 , 471-479. Ferry BL, Welsh KI, Dunn MJ, Law D, Proctor J, Chapel H, Yacoub MH, & Rose ML (1997). Anti-cell surface endothelial antibodies in sera from cardiac and kidney transplant recipients: association with chronic rejection. Transpl Immunol 5 , 17-24. Goodwin AT, Amrani M, Gray CC, Chester AH, & Yacoub MH (1997). Inhibition of endogenous endothelin during cardioplegia improves low coronary reflow following prolonged hypothermic arrest. Eur J Cardiothorac Surg 11 , 981-987. Grocott-Mason RM, Bustami M, Banner N, O'Brien C, Khaghani A, Yacoub M, & Mitchell AG (1997). Influence of allograft coronary artery disease on survival and cardiac function in the decade following orthotopic cardiac transplantation. Transplant Proc 29 , 576-577. Hafizi S, Chester AH, & Yacoub MH (1997). Molecular mechanisms of vascular smooth muscle cell growth. Curr Opin Cardiol 12 , 495-503. Haque T, Thomas JA, Parratt R, Hunt BJ, Yacoub MH, & Crawford DH (1997). A prospective study in heart and lung transplant recipients correlating persistent Epstein-Barr virus infection with clinical events. Transplantation 64 , 1028-1034. Hornick P, Smith J, Pomerance A, Mitchell A, Banner N, Rose M, & Yacoub M (1997). Influence of acute rejection episodes, HLA matching, and donor/recipient phenotype on the development of 'early' transplant-associated coronary artery disease. Circulation 96 , II-53. Hornick P, Smith J, Pomerance A, Banner N, Mitchell A, Rose M, & Yacoub M (1997). Influence of donor/recipient phenotype and degree of HLA mismatch on the development of transplant-associated coronary artery disease in heart transplant patients. Transplant Proc 29 , 1420-1421. Hornick PI, Brookes PA, Mason PD, Taylor KM, Yacoub MH, Rose ML, Batchelor R, & Lechler RI (1997). Optimizing a limiting dilution culture system for quantifying the frequency of interleukin-2-producing alloreactive T helper lymphocytes. Transplantation 64 , 472-479. Hunt BJ, Parratt R, Cable M, Finch D, & Yacoub M (1997). Activation of coagulation and platelets is affected by the hydrophobicity of artificial surfaces. Blood Coagul Fibrinolysis 8 , 223-231. Jenkins GH, Parry DS, Foulsham L, Yacoub MH, & Singer DR (1997). Is cardiac reinnervation in heart transplant recipients functionally significant? Insight from studies of diurnal blood pressure variability and cardiac mass. Transplant Proc 29 , 571. Johnson DL, Rose ML, & Yacoub MH (1997). Immunogenicity of human heart valve endothelial cells and fibroblasts. Transplant Proc 29 , 984-985. Kaprielian RR, Dupont E, Hafizi S, Poole-Wilson PA, Khaghani A, Yacoub MH, & Severs NJ (1997). Angiotensin II receptor type 1 mRNA is upregulated in atria of patients with end-stage heart failure. J Mol Cell Cardiol 29 , 2299-2304. Katayama O, Amrani M, Ledingham S, Jayakumar J, Smolenski RT, Severs N, Rothery S, & Yacoub MH (1997). Effect of cardioplegia infusion pressure on coronary artery endothelium and cardiac mechanical function. Eur J Cardiothorac Surg 11 , 751-762. Katayama O, Ledingham SJ, Amrani M, Smolenski RT, Lachno DR, Jayakumar J, & Yacoub MH (1997). Functional and metabolic effects of adenosine in cardioplegia: role of temperature and concentration. Ann Thorac Surg 63 , 449-454. Khaghani A, Santini F, Dyke CM, Onuzu O, Radley-Smith R, & Yacoub MH (1997). Heterotopic cardiac transplantation in infants and children. J Thorac Cardiovasc Surg 113 , 1042-1048. Khaghani A, Al Kattan KM, Tadjkarimi S, Banner N, & Yacoub M (1997). Early experience with single lung transplantation for emphysema with simultaneous volume reduction of the contralateral lung. Eur J Cardiothorac Surg 11 , 604-608. Knight RA, Kollnberger S, Madden B, Yacoub M, & Hodson ME (1997). Defective antigen presentation by lavage cells from terminal patients with cystic fibrosis. Clin Exp Immunol 107 , 542-547. Krasuski A & Smolenski RT (1997). Cytidine catabolism in staphylococci. Microbios 92 , 199-208. Krasuski A, Galinski J, Smolenski RT, & Marlewski M (1997). [Deamination of adenine and adenosine in staphylococci]. Med Dosw Mikrobiol 49 , 113-122. Latif N, Yacoub MH, & Dunn MJ (1997). Association of pretransplant anti-heart antibodies against human heat shock protein 60 with clinical course following cardiac transplantation. Transplant Proc 29 , 1039-1040. Lazem F, Barbir M, Banner N, Ludman P, Mitchell A, & Yacoub M (1997). Coronary calcification detected by ultrafast computed tomography is a predictor of cardiac events in heart transplant recipients. Transplant Proc 29 , 572-575. Li YY, Maisch B, Rose ML, & Hengstenberg C (1997). Point mutations in mitochondrial DNA of patients with dilated cardiomyopathy. J Mol Cell Cardiol 29 , 2699-2709. Luu TN, Dashwood MR, Tadjkarimi S, Chester AH, & Yacoub MH (1997). ATP-sensitive potassium channels mediate vasodilatation produced by calcitonin gene-related peptide in human internal mammary but not gastroepiploic arteries. Eur J Clin Invest 27 , 960-966. Maiwand MO, Zehr KJ, Dyke CM, Peralta M, Tadjkarimi S, Khagani A, & Yacoub MH (1997). The role of cryotherapy for airway complications after lung and heart-lung transplantation. Eur J Cardiothorac Surg 12 , 549-554. Mankad P & Yacoub M (1997). Influence of basal release of nitric oxide on systolic and diastolic function of both ventricles. J Thorac Cardiovasc Surg 113 , 770-776. Mankad PS, Amrani M, Rothery S, Severs NJ, & Yacoub MH (1997). Relative susceptibility of endothelium and myocardial cells to ischaemia-reperfusion injury. Acta Physiol Scand 161 , 103-112. Marczin N, Riedel B, Royston D, & Yacoub M (1997). Intravenous nitrate vasodilators and exhaled nitric oxide. Lancet 349 , 1742. Marczin N, Riedel B, Gal J, Polak J, & Yacoub M (1997). Exhaled nitric oxide during lung transplantation. Lancet 350 , 1681-1682. McDouall RM, Batten P, McCormack A, Yacoub MH, & Rose ML (1997). MHC class II expression on human heart microvascular endothelial cells: exquisite sensitivity to interferon-gamma and natural killer cells. Transplantation 64 , 1175-1180. Mikhail G, Eadon H, Leaver N, Rogers P, Stephens D, Banner N, Khaghani A, & Yacoub M (1997). An investigation of the pharmacokinetics, toxicity, and clinical efficacy of Neoral cyclosporin in cystic fibrosis patients. Transplant Proc 29 , 599-601. Mikhail G, Al Kattan K, Banner N, Mitchell A, Radley-Smith R, Khaghani A, & Yacoub M (1997). Long-term results of heart-lung transplantation for pulmonary hypertension. Transplant Proc 29 , 633. Mikhail G, Gibbs J, Richardson M, Wright G, Khaghani A, Banner N, & Yacoub M (1997). An evaluation of nebulized prostacyclin in patients with primary and secondary pulmonary hypertension. European Heart Journal 18 , 1499-1504. Morris-Thurgood J, Paul VE, Dyke C, Parry D, Mikhail G, Khaghani A, & Yacoub M (1997). Chronic linkage after heterotopic heart transplantation. Transplant Proc 29 , 580. O'Regan DJ, Borland JA, Chester AH, Pennell DJ, Yacoub M, & Pepper JR (1997). Assessment of human long saphenous vein function with minimally invasive harvesting with the Mayo stripper. Eur J Cardiothorac Surg 12 , 428-435. Parry D, Hextall A, Banner N, Robinson V, & Yacoub M (1997). Pregnancy following lung transplantation. Transplant Proc 29 , 629. Parry DS, Foulsham L, Jenkins G, Wharton J, Marron K, Banner N, & Yacoub M (1997). Incidence and functional significance of sympathetic reinnervation after cardiac transplantation. Transplant Proc 29 , 569-570. Patel VB, Corbett JM, Dunn MJ, Winrow VR, Portmann B, Richardson PJ, & Preedy VR (1997). Protein profiling in cardiac tissue in response to the chronic effects of alcohol. Electrophoresis 18 , 2788-2794. Pepper J & Yacoub M (1997). Valve conserving operation for aortic regurgitation. J Card Surg 12 , 151-156. Petrou M, Bowles C, & Yacoub M (1997). Comparative study of the biomechanical performance of trained and untrained skeletal muscle. Cardiovasc Res 33 , 583-592. Posch A, Chen Z, Dunn MJ, Wheeler CH, Petersen A, Leubner-Metzger G, & Baur X (1997). Latex allergen database. Electrophoresis 18 , 2803-2810. Posch A, Chen Z, Wheeler C, Dunn MJ, Raulf-Heimsoth M, & Baur X (1997). Characterization and identification of latex allergens by two-dimensional electrophoresis and protein microsequencing. J Allergy Clin Immunol 99 , 385-395. Rechavia E, de Silva R, Kushwaha SS, Rhodes CG, Araujo LI, Jones T, Maseri A, & Yacoub MH (1997). Enhanced myocardial 18F-2-fluoro-2-deoxyglucose uptake after orthotopic heart transplantation assessed by positron emission tomography. Journal of the American College of Cardiology 30 , 533-538. Ribadeau DA, Wisnewsky C, Boheler KR, Ter Keurs H, Fiszman MY, & Schwartz K (1997). The sarco(endo)plasmic reticulum Ca(2+)-ATPase gene is regulated at the transcriptional level during compensated left ventricular hypertrophy in the rat. C R Acad Sci III 320 , 963-969. Rose ML (1997). Role of endothelial cells in allograft rejection. Vasc Med 2 , 105-114. Santini F, Dyke C, Edwards S, Stavri G, Feccia M, Khan H, Birks E, & Yacoub MH (1997). Pulmonary autograft versus homograft replacement of the aortic valve: a prospective randomized trial. J Thorac Cardiovasc Surg 113 , 894-899. Saunders MA, Mitchell JA, Seldon PM, Yacoub MH, Barnes PJ, Giembycz MA, & Belvisi MG (1997). Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone. Br J Pharmacol 120 , 545-546. Smith J, Ellis H, Hunt D, Laylor R, Danskine A, Rose M, & Yacoub M (1997). Prospective HLA matching is feasible in thoracic organ transplantation. Transplant Proc 29 , 1467-1468. Smolenski RT, Simmonds HA, & Chambers DJ (1997). Exogenous adenosine, supplied transiently during reperfusion, ameliorates depressed endogenous adenosine production in the post-ischemic rat heart. J Mol Cell Cardiol 29 , 333-346. Sundset A, Tadjkarimi S, Khaghani A, Kvernebo K, & Yacoub MH (1997). Human en bloc double-lung transplantation: bronchial artery revascularization improves airway perfusion. Ann Thorac Surg 63 , 790-795. Sutton CW, Wheeler CH, Sally U, Corbett JM, Cottrell JS, & Dunn MJ (1997). The analysis of myocardial proteins by infrared and ultraviolet laser desorption mass spectrometry. Electrophoresis 18 , 424-431. Taggart DP, Hadjinikolas L, Hooper J, Albert J, Kemp M, Hue D, Yacoub M, & Lincoln JC (1997). Effects of age and ischemic times on biochemical evidence of myocardial injury after pediatric cardiac operations. J Thorac Cardiovasc Surg 113 , 728-735. Takahashi T, Barnes PJ, Kawikova I, Yacoub MH, Warner TD, & Belvisi MG (1997). Contraction of human airway smooth muscle by endothelin-1 and IRL 1620: effect of bosentan. Eur J Pharmacol 324 , 219-222. Townsend PJ, Yacoub MH, & Barton PJ (1997). Assignment of the human cardiac/slow skeletal muscle troponin C gene (TNNC1) between D3S3118 and GCT4B10 on the short arm of chromosome 3 by somatic cell hybrid analysis. Annals of Human Genetics 61 ( Pt 4) , 375-377. Townsend PJ, Yacoub MH, & Barton PJ (1997). Assignment of the human fast skeletal muscle troponin C gene (TNNC2) between D20S721 and GCT10F11 on chromosome 20 by somatic cell hybrid analysis. Annals of Human Genetics 61 ( Pt 5) , 457-459. Webb BL, Lindsay MA, Seybold J, Brand NJ, Yacoub MH, Haddad EB, Barnes PJ, Adcock IM, & Giembycz MA (1997). Identification of the protein kinase C isoenzymes in human lung and airways smooth muscle at the protein and mRNA level. Biochem Pharmacol 54 , 199-205. White RN, Cobb MA, Brownlie SE, Pattison CW, Cumming DV, Jones DG, Williamson HA, & Yacoub MH (1997). Skeletal muscle extra-aortic counterpulsation in dogs with dilated cardiomyopathy. J Small Anim Pract 38 , 554-560. Wong K, Boheler KR, Petrou M, & Yacoub MH (1997). Pharmacological modulation of pressure-overload cardiac hypertrophy: changes in ventricular function, extracellular matrix, and gene expression. Circulation 96 , 2239-2246. Yacoub M & Polak JM (1997). NO prizes. Nature 385 , 385. Yacoub M, Al Kattan KM, Tadjkarimi S, Eren T, & Khaghani A (1997). Medium term results of direct bronchial arterial revascularisation using IMA for single lung transplantation (SLT with direct revascularisation). Eur J Cardiothorac Surg 11 , 1030-1036. Yacoub MH (1997). Hemodynamics of "domino" heart transplantation. The role of ventriculo-ventricular interaction and after load mismatch. G Ital Cardiol 27 , 540-543. Yacoub MH, Khan H, Stavri G, Shinebourne E, & Radley-Smith R (1997). Anatomic correction of the syndrome of prolapsing right coronary aortic cusp, dilatation of the sinus of Valsalva, and ventricular septal defect. J Thorac Cardiovasc Surg 113 , 253-260. Yacoub MH, Gyi K, Khaghani A, Dyke C, Hodson M, Radley-Smith R, & Banner NR (1997). Analysis of 10-year experience with heart-lung transplantation for cystic fibrosis. Transplant Proc 29 , 632. Zhang H, Morgan-Capner P, Latif N, Pandolfino YA, Fan W, Dunn MJ, & Archard LC (1997). Coxsackievirus B3-induced myocarditis. Characterization of stable attenuated variants that protect against infection with the cardiovirulent wild-type strain. Am J Pathol 150 , 2197-2207. |