| Foreword by Professor Sir Magdi Yacoub | ||
| Identity | ||
| Teaching | ||
| Funding | ||
| History | ||
| Management Structure | ||
| How to reach us | ||
| Seminars | ||
| Student Presentation Day 2006 | ||
| Bioengineering the Heart - Royal Society | ||
| New Collaboration with EMBL | ||
Amrani M, Yacoub MH, & Royston D (1999). Myocardial protection for cardiac surgery: classical views and new trends. Int Anesthesiol Clin 37 , 39-53. Baker CS, Hall RJ, Evans TJ, Pomerance A, Maclouf J, Creminon C, Yacoub MH, & Polak JM (1999). Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol 19 , 646-655. Banks RE, Dunn MJ, Forbes MA, Stanley A, Pappin D, Naven T, Gough M, Harnden P, & Selby PJ (1999). The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis--preliminary findings. Electrophoresis 20 , 689-700. Barton PJ, Cullen ME, Townsend PJ, Brand NJ, Mullen AJ, Norman DA, Bhavsar PK, & Yacoub MH (1999). Close physical linkage of human troponin genes: organization, sequence, and expression of the locus encoding cardiac troponin I and slow skeletal troponin T. Genomics 57 , 102-109. Batten P, McCormack AM, Page CS, Yacoub MH, & Rose ML (1999). Human T cell responses to human and porcine endothelial cells are highly sensitive to cyclosporin A and FK506 in vitro. Transplantation 68 , 1552-1560. Birks EJ, Webb C, Child A, Radley-Smith R, & Yacoub MH (1999). Early and long-term results of a valve-sparing operation for Marfan syndrome. Circulation 100 , II29-II35. Buckley MG, Marcus NJ, & Yacoub MH (1999). Cardiac peptide stability, aprotinin and room temperature: importance for assessing cardiac function in clinical practice. Clin Sci (Lond) 97 , 689-695. Bundy R, Marczin N, Chester AH, & Yacoub M (1999). Differential regulation of DNA synthesis by nitric oxide and hydroxyurea in vascular smooth muscle cells. Am J Physiol 277 , H1799-H1807. Burton PB, Yacoub MH, & Barton PJ (1999). Cyclin-dependent kinase inhibitor expression in human heart failure. A comparison with fetal development. European Heart Journal 20 , 604-611. Burton PB, Raff MC, Kerr P, Yacoub MH, & Barton PJ (1999). An intrinsic timer that controls cell-cycle withdrawal in cultured cardiac myocytes. Dev Biol 216 , 659-670. Carr-White GS, Kon M, Koh TW, Glennan S, Ferdinand FD, De Souza AC, Pepper JR, Pennell DJ, Gibson DG, & Yacoub MH (1999). Right ventricular function after pulmonary autograft replacement of the aortic valve. Circulation 100 , II36-II41. Carr-White GS, Glennan S, Edwards S, Ferdinand FD, Desouza AC, Pepper JR, & Yacoub MH (1999). Pulmonary autograft versus aortic homograft for rereplacement of the aortic valve: results from a subset of a prospective randomized trial. Circulation 100 , II103-II106. Davies JM, Hawe N, Kabarowski J, Huang QH, Zhu J, Brand NJ, Leprince D, Dhordain P, Cook M, Morriss-Kay G, & Zelent A (1999). Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene. Oncogene 18 , 365-375. Dunn MJ (1999). Electroblotting of proteins from 2-D polyacrylamide gels. Methods Mol Biol 112 , 313-318. Dunn MJ (1999). Detection of total proteins on western blots of 2-D polyacrylamide gels. Methods Mol Biol 112 , 319-329. Faulk WP, Rose M, Meroni PL, Del Papa N, Torry RJ, Labarrere CA, Busing K, Crisp SJ, Dunn MJ, & Nelson DR (1999). Antibodies to endothelial cells identify myocardial damage and predict development of coronary artery disease in patients with transplanted hearts. Hum Immunol 60 , 826-832. Goldman B, Christakis G, David T, Rakowski H, Bach D, Wood J, Goldman S, Pepper J, Yacoub M, Verrier E, & Petracek M (1999). Will stentless valves be durable? The Toronto valve (TSPV) at 5 to 6 years. Semin Thorac Cardiovasc Surg 11 , 42-49. Goodwin AT, Amrani M, Marchbank AJ, Gray CC, Jayakumar J, & Yacoub MH (1999). Coronary vasoconstriction to endothelin-1 increases with age before and after ischaemia and reperfusion. Cardiovasc Res 41 , 554-562. Gray CC, Amrani M, & Yacoub MH (1999). Heat stress proteins and myocardial protection: experimental model or potential clinical tool? Int J Biochem Cell Biol 31 , 559-573. Haddad EB, Patel H, Keeling JE, Yacoub MH, Barnes PJ, & Belvisi MG (1999). Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pig airways. Br J Pharmacol 127 , 413-420. Hafizi S, Allen SP, Goodwin AT, Chester AH, & Yacoub MH (1999). Endothelin-1 stimulates proliferation of human coronary smooth muscle cells via the ET(A) receptor and is co-mitogenic with growth factors. Atherosclerosis 146 , 351-359. Hafizi S, Chester AH, & Yacoub MH (1999). Inhibition of human cardiac fibroblast mitogenesis by blockade of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Clin Exp Pharmacol Physiol 26 , 511-513. Hasnat K, Birks EJ, Liddicoat J, Hon JK, Edwards S, Glennon S, & Yacoub MH (1999). Patient outcome and valve performance following a second aortic valve homograft replacement. Circulation 100 , II42-II47. Heinke MY, Wheeler CH, Yan JX, Amin V, Chang D, Einstein R, Dunn MJ, & Dos Remedios CG (1999). Changes in myocardial protein expression in pacing-induced canine heart failure. Electrophoresis 20 , 2086-2093. Hoare GS, Marczin N, Chester AH, & Yacoub MH (1999). Role of oxidant stress in cytokine-induced activation of NF-kappaB in human aortic smooth muscle cells. Am J Physiol 277 , H1975-H1984. Jayakumar J, Smolenski RT, Gray CC, Goodwin AT, Amrani M, & Yacoub MH (1999). Effects of heat stress on metabolism of high-energy phosphates. Comparison of normothermic and hypothermic ischemia. J Cardiovasc Surg (Torino) 40 , 481-486. Jin XY, Pepper JR, Gibson DG, & Yacoub MH (1999). Early changes in the time course of myocardial contraction after correcting aortic regurgitation. Ann Thorac Surg 67 , 139-145. Kalsi KK, Zych M, Slominska EM, Kochan Z, Yacoub MH, & Smolenski RT (1999). Adenine incorporation in human and rat endothelium. Biochim Biophys Acta 1452 , 145-150. Kalsi KK, Smolenski RT, Pritchard RD, Khaghani A, Seymour AM, & Yacoub MH (1999). Energetics and function of the failing human heart with dilated or hypertrophic cardiomyopathy. Eur J Clin Invest 29 , 469-477. Kavanagh T, Yacoub MH, Kennedy J, & Austin PC (1999). Return to work after heart transplantation: 12-year follow-up. J Heart Lung Transplant 18 , 846-851. Khaghani A, Casula R, Khan NE, & Yacoub MH (1999). Heterotopic heart transplantation through a right thoracotomy. Ann Thorac Surg 68 , 2334-2336. Kozlowska M, Smolenski RT, Makarewicz W, Hoffmann C, Jastorff B, & Swierczynski J (1999). ATP depletion, purine riboside triphosphate accumulation and rat thymocyte death induced by purine riboside. Toxicol Lett 104 , 171-181. Latif N, Zhang H, Archard LC, Yacoub MH, & Dunn MJ (1999). Characterization of anti-heart antibodies in mice after infection with coxsackie B3 virus. Clin Immunol 91 , 90-98. Latif N, Taylor PM, Khan MA, Yacoub MH, & Dunn MJ (1999). The expression of heat shock protein 60 in patients with dilated cardiomyopathy. Basic Res Cardiol 94 , 112-119. Lawson C, Ainsworth M, Yacoub M, & Rose M (1999). Ligation of ICAM-1 on endothelial cells leads to expression of VCAM-1 via a nuclear factor-kappaB-independent mechanism. J Immunol 162 , 2990-2996. Leyh RG, Schmidtke C, Sievers HH, & Yacoub MH (1999). Opening and closing characteristics of the aortic valve after different types of valve-preserving surgery. Circulation 100 , 2153-2160. Lidington EA, Moyes DL, McCormack AM, & Rose ML (1999). A comparison of primary endothelial cells and endothelial cell lines for studies of immune interactions. Transpl Immunol 7 , 239-246. Ludman PF, Lazem F, Barbir M, & Yacoub M (1999). Incidence and clinical relevance of coronary calcification detected by electron beam computed tomography in heart transplant recipients. European Heart Journal 20 , 303-308. Lund O, Chandrasekaran V, Grocott-Mason R, Elwidaa H, Mazhar R, Khaghani A, Mitchell A, Ilsley C, & Yacoub MH (1999). Primary aortic valve replacement with allografts over twenty-five years: valve-related and procedure-related determinants of outcome. J Thorac Cardiovasc Surg 117 , 77-90. Miraldi F, Barretta A, Yacoub MH, Pazzaglia A, Sani G, & Toscano M (1999). Siena's experience with pulmonary autograft operations: clinical and echocardiographic follow-up. G Ital Cardiol 29 , 1286-1290. Morrell NW, Upton PD, Kotecha S, Huntley A, Yacoub MH, Polak JM, & Wharton J (1999). Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors. Am J Physiol 277 , L440-L448. Owen VJ, Burton PB, Michel MC, Zolk O, Bohm M, Pepper JR, Barton PJ, Yacoub MH, & Harding SE (1999). Myocardial dysfunction in donor hearts. A possible etiology. Circulation 99 , 2565-2570. Pate MA, Chester AH, Crabbe DS, Amrani M, Brown TJ, Roach AG, & Yacoub MH (1999). Characterisation of constrictor endothelin receptors in the human internal thoracic artery and saphenous vein. J Cardiovasc Pharmacol 33 , 567-572. Patel HJ, Belvisi MG, Donnelly LE, Yacoub MH, Chung KF, & Mitchell JA (1999). Constitutive expressions of type I NOS in human airway smooth muscle cells: evidence for an antiproliferative role. FASEB J 13 , 1810-1816. Patel HJ, Venkatesan P, Halfpenny J, Yacoub MH, Fox A, Barnes PJ, & Belvisi MG (1999). Modulation of acetylcholine release from parasympathetic nerves innervating guinea-pig and human trachea by endomorphin-1 and -2. Eur J Pharmacol 374 , 21-24. Petrou M, Clarke S, Morrison K, Bowles C, Dunn M, & Yacoub M (1999). Clenbuterol increases stroke power and contractile speed of skeletal muscle for cardiac assist. Circulation 99 , 713-720. Posch A, Wheeler CH, Chen Z, Flagge A, Dunn MJ, Papenfuss F, Raulf-Heimsoth M, & Baur X (1999). Class I endochitinase containing a hevein domain is the causative allergen in latex-associated avocado allergy. Clin Exp Allergy 29 , 667-672. Ribadeau-Dumas A, Brady M, Boateng SY, Schwartz K, & Boheler KR (1999). Sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2) gene products are regulated post-transcriptionally during rat cardiac development. Cardiovasc Res 43 , 426-436. Rosenthal G, Pomeranz S, Spektor S, Yacoub M, & Israel ZH (1999). Syndrome of overdrainage associated with disconnection of a ventriculoperitoneal shunt. Pediatr Neurosurg 31 , 124-126. Santalucia T, Boheler KR, Brand NJ, Sahye U, Fandos C, Vinals F, Ferre J, Testar X, Palacin M, & Zorzano A (1999). Factors involved in GLUT-1 glucose transporter gene transcription in cardiac muscle. J Biol Chem 274 , 17626-17634. Scheler C, Li XP, Salnikow J, Dunn MJ, & Jungblut PR (1999). Comparison of two-dimensional electrophoresis patterns of heat shock protein Hsp27 species in normal and cardiomyopathic hearts. Electrophoresis 20 , 3623-3628. Schemmer P, Bradford BU, Rose ML, Bunzendahl H, Raleigh JA, Lemasters JJ, & Thurman RG (1999). Intravenous glycine improves survival in rat liver transplantation. Am J Physiol 276 , G924-G932. Smolenska Z, Kaznowska Z, Zarowny D, Simmonds HA, & Smolenski RT (1999). Effect of methotrexate on blood purine and pyrimidine levels in patients with rheumatoid arthritis. Rheumatology (Oxford) 38 , 997-1002. Warraich RS, Dunn MJ, & Yacoub MH (1999). Subclass specificity of autoantibodies against myosin in patients with idiopathic dilated cardiomyopathy: pro-inflammatory antibodies in DCM patients. Biochem Biophys Res Commun 259 , 255-261. Weekes J, Wheeler CH, Yan JX, Weil J, Eschenhagen T, Scholtysik G, & Dunn MJ (1999). Bovine dilated cardiomyopathy: proteomic analysis of an animal model of human dilated cardiomyopathy. Electrophoresis 20 , 898-906. Wheeler MD, Ikejema K, Enomoto N, Stacklewitz RF, Seabra V, Zhong Z, Yin M, Schemmer P, Rose ML, Rusyn I, Bradford B, & Thurman RG (1999). Glycine: a new anti-inflammatory immunonutrient. Cell Mol Life Sci 56 , 843-856. Yacoub M, Onuzo O, Riedel B, & Radley-Smith R (1999). Mobilization of the left and right fibrous trigones for relief of severe left ventricular outflow obstruction. J Thorac Cardiovasc Surg 117 , 126-132. Yacoub MH, Kilner PJ, Birks EJ, & Misfeld M (1999). The aortic outflow and root: a tale of dynamism and crosstalk. Ann Thorac Surg 68 , S37-S43. |