| Foreword by Professor Sir Magdi Yacoub | ||
| Identity | ||
| Teaching | ||
| Funding | ||
| History | ||
| Management Structure | ||
| How to reach us | ||
| Seminars | ||
| Student Presentation Day 2006 | ||
| Bioengineering the Heart - Royal Society | ||
| New Collaboration with EMBL | ||
Publications - 2006 Abunasra H, Smolenski RT, Yap J, Jayakumar J, Sheppard M, & Yacoub MH (2006). Comparison of two gene transfer models for the attenuation of myocardial ischemia-reperfusion injury following preservation for cardiac transplantation. Eur J Cardiothorac Surg29, 772-778. Batten P, Sarathchandra P, Antoniw JW, Tay SS, Lowdell MW, Taylor PM, & Yacoub MH (2006). Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves. Tissue Eng12, 2263-2273. Birks EJ, Tansley PD, Hardy J, George RS, Bowles CT, Burke M, Banner NR, Khaghani A, & Yacoub MH (2006). Left ventricular assist device and drug therapy for the reversal of heart failure. N Engl J Med355, 1873-1884. Boyton RJ, Smith J, Ward R, Jones M, Ozerovitch L, Wilson R, Rose M, Trowsdale J, & Altmann DM (2006). HLA-C and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis. Am J Respir Crit Care Med173, 327-333. Brand NJ, Roy A, Hoare G, Chester A, & Yacoub MH (2006). Cultured interstitial cells from human heart valves express both specific skeletal muscle and non-muscle markers. Int J Biochem Cell Biol38, 30-42. Cecchi F, Olivotto I, Nistri S, Antoniucci D, & Yacoub MH (2006). Midventricular obstruction and clinical decision-making in obstructive hypertrophic cardiomyopathy. Herz31, 871-876. Cullen ME, Yuen AH, Felkin LE, Smolenski RT, Hall JL, Grindle S, Miller LW, Birks EJ, Yacoub MH, & Barton PJ (2006). Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis. Circulation114, I16-I20. De Robertis F, Birks EJ, Rogers P, Dreyfus G, Pepper JR, & Khaghani A (2006). Clinical performance with the Levitronix Centrimag short-term ventricular assist device. J Heart Lung Transplant25, 181-186. Dreger SA, Thomas P, Sachlos E, Chester AH, Czernuszka JT, Taylor PM, & Yacoub MH (2006). Potential for synthesis and degradation of extracellular matrix proteins by valve interstitial cells seeded onto collagen scaffolds. Tissue Eng12, 2533-2540. Edgar AJ, Chacon MR, Bishop AE, Yacoub MH, & Polak JM (2006). Upregulated genes in sporadic, idiopathic pulmonary arterial hypertension. Respir Res7, 1. Felkin LE, Birks EJ, George R, Wong S, Khaghani A, Yacoub MH, & Barton PJ (2006). A quantitative gene expression profile of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) in the myocardium of patients with deteriorating heart failure requiring left ventricular assist device support. J Heart Lung Transplant25, 1413-1419. Felkin LE, Taegtmeyer AB, & Barton PJ (2006). Real-time quantitative polymerase chain reaction in cardiac transplant research. Methods Mol Biol333, 305-330. Fukushima S, Coppen SR, Varela-Carver A, Yamahara K, Sarathchandra P, Smolenski RT, Yacoub MH, & Suzuki K (2006). A novel strategy for myocardial protection by combined antibody therapy inhibiting both P-selectin and intercellular adhesion molecule-1 via retrograde intracoronary route. Circulation114, I251-I256. Fukushima S, Coppen SR, Varela-Carver A, Brindley G, Yamahara K, Sarathchandra P, Yacoub MH, & Suzuki K (2006). Enhanced efficiency of superoxide dismutase-induced cardioprotection by retrograde intracoronary administration. Cardiovasc Res69, 459-465. George RS, Birks EJ, Haj-Yahia S, Bowles CT, Hall A, Khaghani A, & Petrou M (2006). Acinetobacter mediastinitis in a heart transplant patient. Ann Thorac Surg82, 715-716. Gyi KM, Hodson ME, & Yacoub MY (2006). Pregnancy in cystic fibrosis lung transplant recipients: case series and review. J Cyst Fibros5, 171-175. Haj-Yahia SM, Birks EJ, Hardy J, Yacoub MH, & Khaghani A (2006). Minimally invasive technique for explantation of right ventricular assist devices. Ann Thorac Surg82, 1547-1548. Hoare GS, Birks EJ, Bowles C, Marczin N, & Yacoub MH (2006). In vitro endothelial cell activation and inflammatory responses in end-stage heart failure. J Appl Physiol101, 1466-1473. Hornick P & Rose M (2006). Chronic rejection in the heart. Methods Mol Biol333, 131-144. Kalsi K, Marinaki AM, Yacoub MH, & Smolenski RT (2006). HPLC/Tandem Ion Trap Mass Detector Methods for Determination of Inosine Monophosphate Dehydrogenase (IMPDH) and Thiopurine Methyltransferase (TPMT). Nucleosides Nucleotides Nucleic Acids25, 1241-1244. Kelsall CJ, Chester AH, Sarathchandra P, & Singer DR (2006). Expression and localization of C-type natriuretic peptide in human vascular smooth muscle cells. Vascul Pharmacol. 45, 368-373. Ku CH, Johnson PH, Batten P, Sarathchandra P, Chambers RC, Taylor PM, Yacoub MH, & Chester AH (2006). Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch. Cardiovasc Res71, 548-556. Latif N, Sarathchandra P, Taylor PM, Antoniw J, Brand N, & Yacoub MH (2006). Characterization of molecules mediating cell-cell communication in human cardiac valve interstitial cells. Cell Biochem Biophys45, 255-264. Mourkioti F, Kratsios P, Luedde T, Song YH, Delafontaine P, Adami R, Parente V, Bottinelli R, Pasparakis M, & Rosenthal N (2006). Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest116, 2945-2954. Nakamura K, Al-Ruzzeh S, Gray C, Yacoub M, & Amrani M (2006). Effect of myocardial reperfusion on the release of nitric oxide after regional ischemia: an experimental model of beating-heart surgery. Tex Heart Inst J33, 35-39. Newell H, Smith JD, Rogers P, Birks E, Danskine AJ, Fawson RE, & Rose ML (2006). Sensitization following LVAD implantation using leucodepleted blood is not due to HLA antibodies. Am J Transplant6, 1712-1717. Osman L, Chester AH, Amrani M, Yacoub MH, & Smolenski RT (2006). A novel role of extracellular nucleotides in valve calcification: a potential target for atorvastatin. Circulation114, I566-I572. Osman L, Yacoub MH, Latif N, Amrani M, & Chester AH (2006). Role of human valve interstitial cells in valve calcification and their response to atorvastatin. Circulation114, I547-I552. Osman L, Amrani M, Isley C, Yacoub MH, & Smolenski RT (2006). Stimulatory effects of atorvastatin on extracellular nucleotide degradation in human endothelial cells. Nucleosides Nucleotides Nucleic Acids25, 1125-1128. Pepe G, Giusti B, & Yacoub M (2006). An expanding role of biomarkers in acute aortic syndromes. Clin Cardiol29, 432-433. Reed EF, Demetris AJ, Hammond E, Itescu S, Kobashigawa JA, Reinsmoen NL, Rodriguez ER, Rose M, Stewart S, Suciu-Foca N, Zeevi A, & Fishbein MC (2006). Acute antibody-mediated rejection of cardiac transplants. J Heart Lung Transplant25, 153-159. Rosenthal N, Santini MP, & Musaro A (2006). Growth factor enhancement of cardiac regeneration. Cell Transplant15 Suppl 1, S41-S45. Santini MP, Winn N, & Rosenthal N (2006). Signalling pathways in cardiac regeneration. Novartis Found Symp274, 228-238. Santise G, Petrou M, Pepper JR, Dreyfus G, Khaghani A, & Birks EJ (2006). Levitronix as a short-term salvage treatment for primary graft failure after heart transplantation. J Heart Lung Transplant25, 495-498. Slominska EM, Carrey EA, Foks H, Orlewska C, Wieczerzak E, Sowinski P, Yacoub MH, Marinaki AM, Simmonds HA, & Smolenski RT (2006). A Novel Nucleotide Found in Human Erythrocytes, 4-Pyridone-3-carboxamide-1-beta-D-ribonucleoside Triphosphate. J Biol Chem281, 32057-32064. Slominska EM, Kowalik K, Smolenski RT, Szolkiewicz M, Rutkowski P, Rutkowski B, & Swierczynski J (2006). Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. Pediatr Nephrol21, 800-806. Slominska EM, Adamski P, Lipinski M, Swierczynski J, & Smolenski RT (2006). Liquid Chromatographic/Mass Spectrometric Procedure for Measurement of NAD Catabolites in Human and Rat Plasma and Urine. Nucleosides Nucleotides Nucleic Acids25, 1245-1249. Smith JD & Rose M (2006). Detection and clinical relevance of antibodies after transplantation. Methods Mol Biol333, 227-246. Smolenski RT, Khalpey Z, Osborne FN, Yuen A, Slominska EM, Lipinski M, Lavitrano M, Rose M, & Yacoub MH (2006). Species differences of endothelial extracellular nucleotide metabolism and its implications for xenotransplantation. Pharmacol Rep58 Suppl, 118-125. Stagg MA, Coppen SR, Suzuki K, Varela-Carver A, Lee J, Brand NJ, Fukushima S, Yacoub MH, & Terracciano CM (2006). Evaluation of frequency, type, and function of gap junctions between skeletal myoblasts overexpressing connexin43 and cardiomyocytes: relevance to cell transplantation. FASEB J20, 744-746. Taegtmeyer AB , Barton PJ, & Yacoub MH (2006). Genetic association studies: personalized medicine in cardiac transplantation. Nat Clin Pract Cardiovasc Med3, 58-59. Taylor PM, Cass AEG, & Yacoub MH. Extracellular Matrix Scaffolds for Tissue Engineering Heart Valves. Progress in Pediatric Cardiology21, 219-225. 2006. Taylor PM, Sachlos E, Dreger SA, Chester AH, Czernuszka JT, & Yacoub MH (2006). Interaction of human valve interstitial cells with collagen matrices manufactured using rapid prototyping. Biomaterials27, 2733-2737. Terrovitis JV, Bulte JW, Sarvananthan S, Crowe LA, Sarathchandra P, Batten P, Sachlos E, Chester AH, Czernuszka JT, Firmin DN, Taylor PM, & Yacoub MH (2006). Magnetic Resonance Imaging of Ferumoxide-Labeled Mesenchymal Stem Cells Seeded on Collagen Scaffolds-Relevance to Tissue Engineering. Tissue Eng . Warraich RS, Griffiths E, Falconar A, Pabbathi V, Bell C, Angelini G, Suleiman MS, & Yacoub MH (2006). Human cardiac myosin autoantibodies impair myocyte contractility: a cause-and-effect relationship. FASEB J20, 651-660. Yacoub M (2006). Pioneers in cardiology: Sir Magdi Yacoub. Circulation113, f46-f47. Yacoub M, Suzuki K, & Rosenthal N (2006). The future of regenerative therapy in patients with chronic heart failure. Nat Clin Pract Cardiovasc Med3 Suppl 1, S133-S135. Yacoub MH, Klieverik LM, Melina G, Edwards SE, Sarathchandra P, Bogers AJ, Squarcia U, Sani G, van Herwerden LA, & Takkenberg JJ (2006). An evaluation of the Ross operation in adults. J Heart Valve Dis15, 531-539. Yacoub MH (2006). The ross operation - an evolutionary tale. Asian Cardiovasc Thorac Ann14, 1-2. Yuen AH, Khalpey Z, Lavitrano M, McGregor CG, Kalsi KK, Yacoub MH, & Smolenski RT (2006). Differences in activities of the enzymes of nucleotide metabolism and its implications for cardiac xenotransplantation. Nucleosides Nucleotides Nucleic Acids25, 1221-1224.
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